Figure 2.

Vulnerability plus exposure events change the physiological state, but a reserve is present. When the reserve is overtaken, clinical manifestations appear. From http://www.sahsu.org/jubilee_presentations/Anderson.ppt#392,21 webcite, courtesy of R Anderson.

Vineis et al. Environmental Health 2009 8:54   doi:10.1186/1476-069X-8-54
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