|
Regression coefficients and probability values to determine the association between seminal parameters and exposure and time of exposure to methylated OP metabolites. |
||||||
| Exposure to Pesticides (β ± SEM) |
P |
P* adjusted |
Time of exposure to pesticides (β ± SEM) |
P |
P* adjusted |
|
|
|
||||||
| Time of liquefaction minutes |
-1.15 ± 1.73 |
0.51 |
0.84 |
0.17 ± 0.30 |
0.56 |
0.95 |
| Seminal Volume mL |
-0.76 ± 0.32 |
0.02 |
0.12 |
-0.09 ± 0.06 |
0.14 |
0.29 |
| pH |
0.24 ± 0.09 |
0.01 |
0.002 |
0.03 ± 0.02 |
0.08 |
0.001 |
| Log Corrected fructose |
-0.17 ± 0.09 |
0.05 |
0.04 |
-0.04 ± 0.02 |
0.01 |
0.28 |
| Log Seminal zinc |
-0.05 ± 0.09 |
0.61 |
0.40 |
-0.03 ± 0.02 |
0.18 |
0.74 |
| Log sperms/mL |
-0.10 ± 0.12 |
0.43 |
1.00 |
-0.01 ± 0.02 |
0.51 |
0.76 |
| Log sperms/ejaculum |
-0.20 ± 0.12 |
0.171 |
0.5 |
-0.04 ± 0.03 |
0.12 |
0.84 |
| Sperm Vitality % |
2.20 ± 1.79 |
0.22 |
0.05 |
-0.21 ± 0.32 |
0.52 |
0.15 |
| Log motility grade 3 (%) |
-0.03 ± 0.09 |
0.73 |
0.90 |
-0.02 ± 0.01 |
0.18 |
1.00 |
| Log motility grade 3 + 2 (%) |
-0.05 ± 0.05 |
0.38 |
0.52 |
-0.01 ± 0.01 |
0.14 |
0.27 |
| Sperm with normal morphology (%) |
-7.03 ± 2.14 |
0.01 |
0.42 |
-0.86 ± 0.39 |
0.03 |
0.48 |
| Immature sperm (%) |
1.12 ± 1.51 |
0.46 |
1.00 |
0.14 ± 0.27 |
0.61 |
0.98 |
| Log Seminal leucocytes |
0.56 ± 0.09 |
0.01 |
0.68 |
0.02 ± 0.02 |
0.39 |
0.95 |
| Serum testosterone (ng/mL) |
-0.67 ± 0.41 |
0.10 |
0.59 |
-0.10 ± 0.07 |
0.19 |
1.00 |
| Log Serum estradiol (pg/ml) |
0.05 ± 0.07 |
0.45 |
0.21 |
0.03 ± 0.01 |
0.03 |
0.38 |
| Log Serum FSH (mIU/mL) |
-0.13 ± 0.18 |
0.46 |
0.89 |
0.01 ± 0.03 |
0.76 |
1.00 |
| Log Serum LH (mIU/mL) |
-0.40 ± 0.20 |
0.05 |
0.99 |
-0.11 ± 0.04 |
0.01 |
0.97 |
| Log T/E2 (ng/pg) |
-0.12 ± 0.07 |
0.11 |
0.18 |
-0.04 ± 0.01 |
0.01 |
0.56 |
| Log T/LH (ng/mIU) |
0.34 ± 0.20 |
0.09 |
1.00 |
0.10 ± 0.04 |
0.01 |
1.00 |
|
Regressions adjusted for age and alcohol consumption. Exposure to pesticide: 0 = non exposed; 1 = exposed. Ethylated metabolites of OPs: 0 = non detectable; 1 = over limit of detection. Time of exposure to pesticides (continuous variable). β ± SEM: Coefficient of regression ± Standard error of the mean. Data with non parametric behavior were log-transformed in order to performed linear regression analyses. *Holm's test adjustment. +Analyses were performed after controlling for urine levels of methylated OP metabolites, respectively. | ||||||
Yucra et al. Environmental Health 2008 7:59 doi:10.1186/1476-069X-7-59 |
||||||