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Behavior of mice fed with mercury-containing diets in the cross maze test. a |
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| Diet (Hg dose in food expressed in ng/g) |
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| Behavioral measures |
Control diet (n = 6) |
5.4 (n = 8) |
62 (n = 8) |
520 (n = 8) |
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| Number of entries into open arms, % |
28 ± 3.5 |
**13.7 ± 4.2 |
*21 ± 2.6 |
26.3 ± 3 |
| Time spent in open arms, % |
20.4 ± 2.9 |
*7.7 ± 2.9 |
*8.7 ± 1.6 |
14.7 ± 3.8 |
| Time spent at the extremity of open arms, (sec) |
30.9 ± 8.7 |
*13.4 ± 6.8 |
*14.6 ± 3.4 |
23.6 ± 8.7 |
| Number of entries into closed arms, % |
71.5 ± 4.2 |
**86.3 ± 4.2 |
*79 ± 2.6 |
73.7 ± 3 |
| Time spent in closed arms, % |
41.4 ± 2.8 |
**61.5 ± 4.3 |
**61 ± 2.6 |
49.4 ± 3.9 |
| Time spent at the extremity of closed arms, (sec) |
112.4 ± 13.6 |
**159.1 ± 14.2 |
**158.3 ± 8.5 |
116.5 ± 11.2 |
| Time spent in center, % |
38.3 ± 2 |
*31 ± 2.2 |
**30.2 ± 1.7 |
36.3 ± 1.7 |
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a Results are expressed as the mean ± SE. Significant differences are indicated by an asterisk (p < 0.05), or two (p < 0.01). | ||||
Bourdineaud et al. Environmental Health 2008 7:53 doi:10.1186/1476-069X-7-53 |
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