Figure 5.

Block diagram to show primary (black arrows) and secondary (white arrows) asbestos fibers translocation. Size of arrows for secondary translocation are representative of accumulation. Accumulation increases in proportion to blood perfusion (lung, kidney and liver) and microvascular permeability (liver), while it is lower in brain and pleural space due to low permeability of the blood-brain barrier and of the endothelial-parietal mesothelium complex, respectively.