Table 1 |
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|
Reproductive outcomes investigated in the Swedish Fishermen's Families Cohorts. |
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|
Exposure |
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|
Unit of observation |
Outcome1 |
Cohort affiliation |
Childhood exposure2 |
Fish consumption |
CB-1533 |
p,p'-DDE4 |
|
|
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|
Man |
Sperm motility |
- |
- |
- |
↓ [16] |
↓ [16] |
|
Sperm concentration |
- |
- |
- |
0 [16] |
0 [16] |
|
|
Semen volume |
- |
- |
- |
0 [16] |
0 [16] |
|
|
Total sperm count |
- |
- |
- |
0 [16] |
0 [16] |
|
|
Sperm chromatin integrity |
- |
- |
- |
↓ [20] |
(↓) [20] |
|
|
Y:X chromosome ratio |
- |
- |
- |
↓ [21] |
↓ [21] |
|
|
Seminal levels of markers of epididymal and accessory sex gland function |
- |
- |
- |
0 [19] |
0 [19] |
|
|
Hormone parameters |
- |
- |
- |
0 [16] |
0 [16] |
|
|
Woman |
Age at menarche |
0 [38] |
↓ [38] |
- |
- |
- |
|
Menstrual cycle length |
↓ [91] |
0 [91] |
(↓) [91] |
0 [91] |
- |
|
|
Miscarriages and stillbirths |
NC [17, 25, 40] |
0 [25, 40] |
0 [25] |
NC [26, 40] |
- |
|
|
Couple |
Time to pregnancy |
NC [24, 25] |
0 [24, 25] |
0 [24, 25] |
0 [26, 33] |
- |
|
Infant/child |
Birth weight |
↓ [14, 17] |
↓ [41] |
↓ [41] |
↓ [31] |
- |
|
Birth length |
0 [14, 17] |
- |
- |
- |
- |
|
|
Head circumference |
↓ [14, 17] |
- |
- |
- |
- |
|
|
Gender ratio |
NC [14, 17] |
- |
- |
- |
- |
|
|
Malformations |
0 [17, 43] |
- |
- |
- |
- |
|
|
|
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|
1 Arrows indicate the effect associated with each exposure, with parenthesis for those effects not found to be of a noteworthy size but not statistically significant. A "0" means that no effect was found, and "NC" signifies non conclusive results. 2 Growing up in a fisherman's family and/or fishing village 3 2,2',4,4',5,5'-hexachlorobiphenyl 4 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene |
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|
Axmon et al. Environmental Health 2008 7:20 doi:10.1186/1476-069X-7-20 |
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