Table 5

Associations between land use in recharge areas for homogenous drinking water supplies and breast cancer.

Fraction of Recharge Area in Specified Land Use
Cases
Controls
Adjusted OR (95% CI)a
Adjusted OR (95% CI)b

Residential
0 to < .5
201
211
1.0 (reference)
1.0 (reference)
.5 to < 1
234
184
1.4 (1.0–1.9)
1.1 (0.8–1.6)
1 to < 1.5
139
122
1.2 (0.8–1.6)
0.9 (0.6–1.3)
1.5 to < 2
99
90
1.2 (0.8–1.7)
0.9 (0.6–1.4)
≥ 2
9
16
0.7 (0.3–1.6)
0.5 (0.2–1.2)
Commercial
0 to < .5
587
533
1.0 (reference)
1.0 (reference)
.5 to < 1
49
54
0.9 (0.6–1.4)
0.8 (0.5–1.3)
1 to < 1.5
12
8
1.6 (0.6–4.1)
1.7 (0.7–4.4)
1.5 to < 2
10
7
1.4 (0.5–3.9)
1.4 (0.5–3.7)
2 to < 2.5
7
3
2.6 (0.6–10.3)
2.3 (0.6–9.3)
2.5 to < 3
17
18
1.0 (0.5–2.0)
0.9 (0.4–1.8)
Pesticide application area
0 to < .5
234
243
1.0 (reference)
1.0 (reference)
.5 to < 1
178
140
1.3 (1.0–1.8)
1.2 (0.8–1.6)
1 to < 1.5
229
203
1.2 (0.9–1.6)
0.9 (0.7–1.4)
≥ 1.5
41
37
1.2 (0.7–2.0)
0.9 (0.5–1.6)
Totalc
0 to < .5
70
93
1.0 (reference)
1.0 (reference)
.5 to < 1
87
72
1.7 (1.1–2.6)
1.5 (0.9–2.4)
1 to < 1.5
69
64
1.5 (0.9–2.4)
1.3 (0.7–2.2)
1.5 to < 2
90
81
1.6 (1.0–2.6)
1.3 (0.7–2.3)
2 to < 2.5
187
149
1.9 (1.3–2.8)
1.4 (0.8–2.6)
2.5 to < 3
46
40
1.5 (0.9–2.6)
1.2 (0.6–2.3)
3 to < 3.5
98
87
1.7 (1.1–2.6)
1.2 (0.6–2.4)
≥ 3.5
35
37
1.4 (0.8–2.5)
1.0 (0.5–2.2)

a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education.

b Adjusted for variables in analysis [a] and years on Cape Cod and years on the Cape squared.

c Residential plus pesticide use area plus commercial.

Brody et al. Environmental Health: A Global Access Science Source 2006 5:28   doi:10.1186/1476-069X-5-28