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Associations between land use in recharge areas for homogenous drinking water supplies and breast cancer. |
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| Fraction of Recharge Area in Specified Land Use |
Cases |
Controls |
Adjusted OR (95% CI)a |
Adjusted OR (95% CI)b |
|
|
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| Residential |
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| 0 to < .5 |
201 |
211 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
234 |
184 |
1.4 (1.0–1.9) |
1.1 (0.8–1.6) |
| 1 to < 1.5 |
139 |
122 |
1.2 (0.8–1.6) |
0.9 (0.6–1.3) |
| 1.5 to < 2 |
99 |
90 |
1.2 (0.8–1.7) |
0.9 (0.6–1.4) |
| ≥ 2 |
9 |
16 |
0.7 (0.3–1.6) |
0.5 (0.2–1.2) |
| Commercial |
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| 0 to < .5 |
587 |
533 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
49 |
54 |
0.9 (0.6–1.4) |
0.8 (0.5–1.3) |
| 1 to < 1.5 |
12 |
8 |
1.6 (0.6–4.1) |
1.7 (0.7–4.4) |
| 1.5 to < 2 |
10 |
7 |
1.4 (0.5–3.9) |
1.4 (0.5–3.7) |
| 2 to < 2.5 |
7 |
3 |
2.6 (0.6–10.3) |
2.3 (0.6–9.3) |
| 2.5 to < 3 |
17 |
18 |
1.0 (0.5–2.0) |
0.9 (0.4–1.8) |
| Pesticide application area |
||||
| 0 to < .5 |
234 |
243 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
178 |
140 |
1.3 (1.0–1.8) |
1.2 (0.8–1.6) |
| 1 to < 1.5 |
229 |
203 |
1.2 (0.9–1.6) |
0.9 (0.7–1.4) |
| ≥ 1.5 |
41 |
37 |
1.2 (0.7–2.0) |
0.9 (0.5–1.6) |
| Totalc |
||||
| 0 to < .5 |
70 |
93 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
87 |
72 |
1.7 (1.1–2.6) |
1.5 (0.9–2.4) |
| 1 to < 1.5 |
69 |
64 |
1.5 (0.9–2.4) |
1.3 (0.7–2.2) |
| 1.5 to < 2 |
90 |
81 |
1.6 (1.0–2.6) |
1.3 (0.7–2.3) |
| 2 to < 2.5 |
187 |
149 |
1.9 (1.3–2.8) |
1.4 (0.8–2.6) |
| 2.5 to < 3 |
46 |
40 |
1.5 (0.9–2.6) |
1.2 (0.6–2.3) |
| 3 to < 3.5 |
98 |
87 |
1.7 (1.1–2.6) |
1.2 (0.6–2.4) |
| ≥ 3.5 |
35 |
37 |
1.4 (0.8–2.5) |
1.0 (0.5–2.2) |
|
a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education. b Adjusted for variables in analysis [a] and years on Cape Cod and years on the Cape squared. c Residential plus pesticide use area plus commercial. | ||||
Brody et al. Environmental Health: A Global Access Science Source 2006 5:28 doi:10.1186/1476-069X-5-28 |
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