Table 4

Associations between land use in recharge areas for drinking water wells and breast cancer.

Fraction of Recharge Area in Specified Land Use
Cases
Controls
Adjusted OR (95% CI)a
Adjusted OR (95% CI)b

Residential
0 to < .5
252
262
1.0 (reference)
1.0 (reference)
.5 to < 1
243
195
1.3 (1.0–1.7)
1.1 (0.8–1.5)
1 to < 1.5
157
136
1.2 (0.9–1.6)
0.9 (0.7–1.3)
1.5 to < 2
125
106
1.3 (0.9–1.7)
1.0 (0.7–1.4)
≥ 2
47
46
1.1 (0.7–1.7)
0.8 (0.5–1.4)
Commercial
0 to < .5
671
611
1.0 (reference)
1.0 (reference)
.5 to < 1
58
61
0.9 (0.6–1.4)
0.8 (0.6–1.3)
1 to < 1.5
17
16
1.1 (0.5–2.2)
1.2 (0.6–2.4)
1.5 to < 2
19
11
1.7 (0.8–3.7)
1.7 (0.8–3.6)
2 to < 2.5
10
5
2.1 (0.7–6.4)
2.0 (0.7–6.2)
2.5 to < 3
25
22
1.2 (0.7–2.2)
1.1 (0.6–2.0)
≥ 3
24
19
1.2 (0.6–2.2)
1.0 (0.5–1.9)
Pesticide application area
0 to < .5
303
309
1.0 (reference)
1.0 (reference)
.5 to < 1
240
187
1.3 (1.0–1.7)
1.1 (0.8–1.5)
1 to < 1.5
238
211
1.2 (0.9–1.6)
0.9 (0.7–1.3)
≥ 1.5
43
38
1.2 (0.8–2.0)
1.0 (0.6–1.6)
Totalc
0 to < .5
86
112
1.0 (reference)
1.0 (reference)
.5 to < 1
120
101
1.6 (1.1–2.4)
1.4 (0.9–2.2)
1 to < 1.5
75
72
1.4 (0.9–2.2)
1.2 (0.8–2.0)
1.5 to < 2
95
84
1.6 (1.0–2.4)
1.3 (0.8–2.2)
2 to < 2.5
196
155
1.8 (1.2–2.6)
1.4 (0.8–2.4)
2.5 to < 3
51
48
1.4 (0.9–2.4)
1.1 (0.6–2.1)
3 to < 3.5
109
97
1.6 (1.1–2.4)
1.2 (0.7–2.2)
≥ 3.5
92
76
1.7 (1.1–2.7)
1.4 (0.8–2.4)

a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education.

b Adjusted for variables in analysis [a] and years on Cape Cod and years on the Cape squared.

c Residential plus pesticide use area plus commercial.

Brody et al. Environmental Health: A Global Access Science Source 2006 5:28   doi:10.1186/1476-069X-5-28