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Associations between land use in recharge areas for drinking water wells and breast cancer. |
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| Fraction of Recharge Area in Specified Land Use |
Cases |
Controls |
Adjusted OR (95% CI)a |
Adjusted OR (95% CI)b |
|
|
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| Residential |
||||
| 0 to < .5 |
252 |
262 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
243 |
195 |
1.3 (1.0–1.7) |
1.1 (0.8–1.5) |
| 1 to < 1.5 |
157 |
136 |
1.2 (0.9–1.6) |
0.9 (0.7–1.3) |
| 1.5 to < 2 |
125 |
106 |
1.3 (0.9–1.7) |
1.0 (0.7–1.4) |
| ≥ 2 |
47 |
46 |
1.1 (0.7–1.7) |
0.8 (0.5–1.4) |
| Commercial |
||||
| 0 to < .5 |
671 |
611 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
58 |
61 |
0.9 (0.6–1.4) |
0.8 (0.6–1.3) |
| 1 to < 1.5 |
17 |
16 |
1.1 (0.5–2.2) |
1.2 (0.6–2.4) |
| 1.5 to < 2 |
19 |
11 |
1.7 (0.8–3.7) |
1.7 (0.8–3.6) |
| 2 to < 2.5 |
10 |
5 |
2.1 (0.7–6.4) |
2.0 (0.7–6.2) |
| 2.5 to < 3 |
25 |
22 |
1.2 (0.7–2.2) |
1.1 (0.6–2.0) |
| ≥ 3 |
24 |
19 |
1.2 (0.6–2.2) |
1.0 (0.5–1.9) |
| Pesticide application area |
||||
| 0 to < .5 |
303 |
309 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
240 |
187 |
1.3 (1.0–1.7) |
1.1 (0.8–1.5) |
| 1 to < 1.5 |
238 |
211 |
1.2 (0.9–1.6) |
0.9 (0.7–1.3) |
| ≥ 1.5 |
43 |
38 |
1.2 (0.8–2.0) |
1.0 (0.6–1.6) |
| Totalc |
||||
| 0 to < .5 |
86 |
112 |
1.0 (reference) |
1.0 (reference) |
| .5 to < 1 |
120 |
101 |
1.6 (1.1–2.4) |
1.4 (0.9–2.2) |
| 1 to < 1.5 |
75 |
72 |
1.4 (0.9–2.2) |
1.2 (0.8–2.0) |
| 1.5 to < 2 |
95 |
84 |
1.6 (1.0–2.4) |
1.3 (0.8–2.2) |
| 2 to < 2.5 |
196 |
155 |
1.8 (1.2–2.6) |
1.4 (0.8–2.4) |
| 2.5 to < 3 |
51 |
48 |
1.4 (0.9–2.4) |
1.1 (0.6–2.1) |
| 3 to < 3.5 |
109 |
97 |
1.6 (1.1–2.4) |
1.2 (0.7–2.2) |
| ≥ 3.5 |
92 |
76 |
1.7 (1.1–2.7) |
1.4 (0.8–2.4) |
|
a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education. b Adjusted for variables in analysis [a] and years on Cape Cod and years on the Cape squared. c Residential plus pesticide use area plus commercial. | ||||
Brody et al. Environmental Health: A Global Access Science Source 2006 5:28 doi:10.1186/1476-069X-5-28 |
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