|
Associations between wastewater impacted public drinking water in homogenous supplies and breast cancer. |
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| Cases |
Controls |
Adjusted OR (95% CI)a |
Adjusted OR (95% CI)b |
|
|
|
||||
| Average annual excess nitrate-N concentration (mg/L) |
||||
| 0 to < .3 |
280 |
250 |
1.0 (referent) |
1.0 (referent) |
| .3 to < .6 |
163 |
141 |
1.0 (0.7 – 1.3) |
1.0 (0.7 – 1.3) |
| .6 to < .9 |
149 |
144 |
0.9 (0.6 – 1.2) |
0.9 (0.6 – 1.2) |
| .9 to < 1.2 |
78 |
79 |
0.8 (0.5 – 1.2) |
0.8 (0.5 – 1.2) |
| ≥ 1.2 |
12 |
9 |
1.2 (0.5 – 2.9) |
1.2 (0.5 – 3.1) |
| Sum of annual excess nitrate-N concentrations (mg/L) |
||||
| 0 to < .01 |
18 |
17 |
0.8 (0.4 – 1.6) |
0.9 (0.4 – 1.9) |
| .01 to < .1 |
43 |
41 |
0.9 (0.5 – 1.4) |
1.0 (0.6 – 1.7) |
| .1 to < 1 |
104 |
104 |
0.9 (0.6 – 1.2) |
1.1 (0.8 – 1.5) |
| 1 to < 10 |
390 |
344 |
1.0 (referent) |
1.0 (referent) |
| ≥ 10 |
127 |
117 |
1.0 (0.7 – 1.3) |
0.9 (0.6 – 1.2) |
| Number of years exposed to excess nitrate-N > 1 mg/L |
||||
| 0 |
479 |
433 |
1.0 (referent) |
1.0 (referent) |
| < 2 |
50 |
47 |
0.9 (0.6 – 1.4) |
1.0 (0.6 – 1.5) |
| 2 to < 4 |
87 |
69 |
1.1 (0.7 – 1.6) |
1.0 (0.7 – 1.5) |
| 4 to < 6 |
66 |
74 |
0.8 (0.5 – 1.2) |
0.7 (0.5 – 1.1) |
|
a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education. b Adjusted for variables in analysis [a] and years on Cape Cod and years on the Cape squared. | ||||
Brody et al. Environmental Health: A Global Access Science Source 2006 5:28 doi:10.1186/1476-069X-5-28 |
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