|
Associations between wastewater impacted public drinking water and breast cancer. |
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| Cases |
Controls |
Adjusted OR (95% CI)a |
Adjusted OR (95% CI)b |
||
|
|
|||||
| Average annual excess nitrate-N concentration (mg/L) |
|||||
| 0 to < .3 |
327 |
287 |
1.0 (reference) |
1.0 (reference) |
|
| .3 to < .6 |
201 |
175 |
1.0 (0.7 – 1.3) |
0.9 (0.7 – 1.3) |
|
| .6 to < .9 |
155 |
152 |
0.9 (0.6 – 1.2) |
0.8 (0.6 – 1.1) |
|
| .9 to < 1.2 |
120 |
112 |
0.9 (0.6 – 1.2) |
0.9 (0.6 – 1.2) |
|
| ≥ 1.2 |
21 |
19 |
0.9 (0.5 – 1.7) |
1.0 (0.5 – 1.9) |
|
| Sum of annual excess nitrate-N concentrations (mg/L) |
|||||
| 0 to < .01 |
19 |
18 |
0.8 (0.4 – 1.6) |
0.9 (0.5 – 1.9) |
|
| .01 to < .1 |
45 |
42 |
0.9 (0.6 – 1.5) |
1.1 (0.7 – 1.7) |
|
| .1 to < 1 |
119 |
118 |
0.9 (0.7 – 1.2) |
1.1 (0.8 – 1.5) |
|
| 1 to < 10 |
474 |
418 |
1.0 (reference) |
1.0 (reference) |
|
| ≥ 10 |
167 |
149 |
1.0 (0.8 – 1.3) |
0.9 (0.7 – 1.2) |
|
| Number of years exposed to excess nitrate-N > 1 mg/L |
|||||
| 0 |
562 |
504 |
1.0 (reference) |
1.0 (reference) |
|
| < 2 |
58 |
52 |
1.0 (0.7 – 1.5) |
1.1 (0.7 – 1.6) |
|
| 2 to < 4 |
93 |
77 |
1.0 (0.7 – 1.4) |
1.0 (0.7 – 1.4) |
|
| 4 to < 6 |
36 |
44 |
0.8 (0.5 – 1.2) |
0.7 (0.5 – 1.2) |
|
| 6 to < 8 |
50 |
43 |
1.0 (0.6 – 1.5) |
0.9 (0.6 – 1.4) |
|
| ≥ 8 |
25 |
25 |
0.9 (0.5 – 1.7) |
0.9 (0.5 – 1.5) |
|
| OR odds ratio. CI confidence interval. |
|||||
|
a Adjusted for diagnosis/reference year, age at diagnosis/reference year, birth decade, study, vital status, previous breast cancer diagnosis, age at first birth, family history of breast cancer, and education. b Adjusted for variables in analysis (a), years on Cape Cod and years on the Cape squared. | |||||
Brody et al. Environmental Health: A Global Access Science Source 2006 5:28 doi:10.1186/1476-069X-5-28 |
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